Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.86 |
| ▸ | LMNA | P02545 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CDK8 | P49336 | 2/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553557 | 0.87 | ROCK2 (0.67) | GLALMNAKMT2AMEN1HTT | |
| SCHEMBL1553555 | 0.87 | ROCK2 (0.67) | GLALMNAKMT2AMEN1HTT | |
| SCHEMBL9617879 | 0.87 | ROCK2 (0.67) | GLALMNAKMT2AMEN1HTT | |
| SCHEMBL7520976 | 0.79 | ROCK2 (0.76) | GLALMNAKMT2AMEN1HTT | |
| SCHEMBL30828553 | 0.79 | ROCK2 (0.76) | GLALMNAKMT2AMEN1HTT | |
| SCHEMBL13972925 | 0.78 | KMT2A (0.60) | GLALMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13203867 | 0.78 | GLA (0.70) | GLALMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10114127 | 0.78 | GLA (0.70) | GLALMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10113353 | 0.78 | GLA (0.70) | GLALMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14424263 | 0.78 | GLA (0.70) | GLALMNAKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |