Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.67 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.67 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.67 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CHUK | O15111 | 1/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | CDK1 | P06493 | 1/20 | 0.67 |
| ▸ | CDK2 | P24941 | 1/20 | 0.67 |
| ▸ | LTK | P29376 | 1/20 | 0.67 |
| ▸ | CDK8 | P49336 | 1/20 | 0.67 |
| ▸ | PRKX | P51817 | 1/20 | 0.67 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.67 |
| ▸ | STK3 | Q13188 | 1/20 | 0.67 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.67 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553557 | 1.00 | ROCK2 (0.67) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL1553555 | 1.00 | ROCK2 (0.67) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL30828553 | 0.91 | ROCK2 (0.76) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL7520976 | 0.91 | ROCK2 (0.76) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Hydrochloric Acid SCHEMBL27545321 | 0.90 | ROCK2 (0.73) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL13972700 | 0.87 | GLA (0.86) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL30828597 | 0.85 | ACVRL1 (0.72) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL22273261 | 0.84 | ROCK2 (0.63) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL29129855 | 0.83 | ROCK2 (0.70) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL29129852 | 0.83 | ROCK2 (0.70) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4273821-A | — | — | None | — | — | JP | disclosed |
| JP-H04273821-A | ASTHMA THERAPEUTIC DRUG | YOSHITOMI PHARMACEUT IND LTD | 1992-09-30 | — | — | JP | disclosed |