Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10134489 | 0.89 | ALDH1A1 (0.46) | ALDH1A1LMNAHDAC6CYP1A2CYP2D6 | |
| SCHEMBL10115243 | 0.84 | L3MBTL1 (0.56) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113832 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNAHDAC6CYP1A2MEN1 | |
| SCHEMBL10115477 | 0.84 | HDAC6 (0.48) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10113835 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAHDAC6CYP1A2CYP2D6 | |
| SCHEMBL10113721 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL10115197 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNAHDAC6MEN1KMT2A | |
| SCHEMBL13973541 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHDAC6CYP1A2CYP2D6 | |
| SCHEMBL13370602 | 0.82 | ALDH1A1 (0.48) | ALDH1A1LMNAHDAC6CYP1A2CYP2D6 | |
| SCHEMBL10113729 | 0.82 | HDAC6 (0.53) | ALDH1A1LMNAHDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |