Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 3/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27268063 | 0.81 | RIPK1 (0.41) | PARP15PARP10PARP2RIPK1NOS3 | |
| SCHEMBL13105734 | 0.77 | CXCR5 (0.37) | PARP15PARP10PARP2CXCR5SCN5A | |
| SCHEMBL16372678 | 0.76 | MEN1 (0.42) | SCN5AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11936039 | 0.73 | PTGER4 (0.33) | CXCR5CNR2ALDH1A1HTT | |
| SCHEMBL16046454 | 0.73 | HTR2C (0.40) | RIPK1CNR2NOS3NOS1NOS2 | |
| SCHEMBL12432327 | 0.72 | PARP10 (0.46) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL28474252 | 0.72 | RIPK1 (0.47) | RIPK1ALDH1A1HTR2C | |
| SCHEMBL11935508 | 0.72 | PTGER4 (0.41) | CXCR5CNR2 | |
| SCHEMBL13439251 | 0.72 | PTGER4 (0.41) | CXCR5CNR2 | |
| SCHEMBL27842342 | 0.72 | CXCR5 (0.44) | PARP15PARP10PARP2CXCR5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |