Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21694298 | 0.95 | RIPK1 (0.48) | RIPK1MCHR1CYP3A4TSHRPIK3CA | |
| SCHEMBL21694239 | 0.91 | RIPK1 (0.41) | RIPK1MCHR1CYP3A4TSHRPIK3CA | |
| SCHEMBL21694015 | 0.90 | RIPK1 (0.43) | RIPK1MCHR1TSHRHTR2C | |
| SCHEMBL21694076 | 0.86 | CBX7 (0.39) | RIPK1MCHR1 | |
| SCHEMBL27268063 | 0.84 | RIPK1 (0.41) | RIPK1MCHR1HTR2CHTR2AHTR2B | |
| SCHEMBL10503371 | 0.82 | MCHR1 (0.48) | RIPK1MCHR1HTR2CDHFRDCPS | |
| SCHEMBL23493020 | 0.82 | ALDH1A1 (0.53) | RIPK1MCHR1HTR2CDHFRDCPS | |
| SCHEMBL3798519 | 0.82 | ALDH1A1 (0.53) | RIPK1MCHR1HTR2CDHFRDCPS | |
| SCHEMBL1157582 | 0.80 | RIPK1 (0.45) | RIPK1MCHR1HTR2CDHFRDCPS | |
| SCHEMBL21694263 | 0.80 | RIPK1 (0.46) | RIPK1MCHR1HTR2CDHFRDCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108059613-B | Pyrazole amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-108069905-B | Pyrazole amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-04 | — | — | CN | disclosed |