Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113379 | 0.85 | HDAC1 (0.57) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL10112840 | 0.83 | HPGD (0.56) | HDAC3HDAC1HDAC2HDAC6POLB | |
| SCHEMBL10113004 | 0.82 | HPGD (0.55) | HDAC3HDAC1HDAC2HDAC6POLB | |
| SCHEMBL14137556 | 0.79 | MAPT (0.50) | HDAC3HDAC1HDAC6KMT2AMEN1 | |
| SCHEMBL10113022 | 0.79 | HPGD (0.57) | HDAC3HDAC1HDAC2HDAC6POLB | |
| SCHEMBL13716396 | 0.79 | MAPT (0.47) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13716737 | 0.78 | HDAC6 (0.60) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL13716773 | 0.77 | MEN1 (0.46) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL10113406 | 0.75 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL5368440 | 0.75 | HDAC3 (0.62) | HDAC3HDAC1HDAC2HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |