Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13973006 | 0.87 | RAB9A (0.68) | HTR2BNPC1RAB9APKMLMNA | |
| SCHEMBL24166611 | 0.84 | NPC1 (0.62) | HTR2BNPC1RAB9APKMALOX15 | |
| SCHEMBL3546724 | 0.84 | RAB9A (0.70) | NPC1RAB9ALMNASMN1; SMN2EPHX1 | |
| SCHEMBL12156569 | 0.82 | RAB9A (0.67) | NPC1RAB9ASMYD3LMNASMN1; SMN2 | |
| SCHEMBL11936013 | 0.82 | EPHX1 (0.55) | HTR2BNPC1RAB9ASMYD3L3MBTL1 | |
| SCHEMBL7233871 | 0.81 | RAB9A (0.68) | HTR2BNPC1RAB9APKML3MBTL1 | |
| SCHEMBL30426826 | 0.81 | RAB9A (0.68) | HTR2BNPC1RAB9APKML3MBTL1 | |
| SCHEMBL3771394 | 0.81 | RAB9A (0.68) | HTR2BNPC1RAB9APKML3MBTL1 | |
| SCHEMBL6326321 | 0.81 | RAB9A (0.68) | HTR2BNPC1RAB9APKML3MBTL1 | |
| SCHEMBL3771296 | 0.80 | NPC1 (0.64) | HTR2BNPC1RAB9APKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |