Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546724 | 0.91 | RAB9A (0.70) | RAB9AEPHX1GAAKMT2ALMNA | |
| SCHEMBL12156569 | 0.89 | RAB9A (0.67) | RAB9AEPHX1GAAKMT2AMEN1 | |
| SCHEMBL13973019 | 0.87 | HTR2B (0.62) | RAB9AEPHX1GAAKMT2AMEN1 | |
| SCHEMBL12156531 | 0.86 | RAB9A (0.62) | RAB9AEPHX1GAAKMT2AMEN1 | |
| SCHEMBL28927984 | 0.83 | RAB9A (0.64) | RAB9AEPHX1KMT2AMEN1LMNA | |
| SCHEMBL11936004 | 0.82 | EPHX1 (0.60) | RAB9AEPHX1GAAKMT2ALMNA | |
| SCHEMBL28648060 | 0.82 | EPHX1 (0.68) | RAB9AEPHX1GAAKMT2AMEN1 | |
| SCHEMBL3442327 | 0.82 | RAB9A (0.62) | RAB9AKMT2AMEN1LMNAPOLB | |
| SCHEMBL30583805 | 0.82 | RAB9A (0.62) | RAB9AKMT2AMEN1LMNAPOLB | |
| SCHEMBL520877 | 0.82 | NPC1 (0.82) | RAB9AKMT2ALMNANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |