Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28212694 | 0.76 | MTNR1A (0.72) | MTNR1AMTNR1BF13A1TGM2GAA | |
| SCHEMBL12882777 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BF13A1TGM2MGLL | |
| SCHEMBL13203761 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BF13A1TGM2MGLL | |
| SCHEMBL10113212 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BF13A1TGM2MGLL | |
| SCHEMBL6392968 | 0.74 | MITF (0.69) | F13A1TGM2MITFALDH1A1POLB | |
| SCHEMBL10114019 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BF13A1TGM2MGLL | |
| SCHEMBL4720318 | 0.74 | MTNR1A (0.82) | MTNR1AMTNR1BMGLLGAAALDH1A1 | |
| SCHEMBL14433478 | 0.73 | F10 (0.58) | MGLLPOLBHTTLIMK2F10 | |
| SCHEMBL345624 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BGAAALDH1A1HTT | |
| SCHEMBL19494423 | 0.73 | MTNR1A (0.64) | MTNR1AMTNR1BGAAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014285-A1 | NPYY5 antagonists | Shionogi&Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |