Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 6/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964880 | 0.83 | KDM4E (0.39) | HASPINDYRK2ARKDM4EHSD17B10 | |
| SCHEMBL13974159 | 0.82 | HASPIN (0.38) | HASPINDYRK2DYRK1AGRM2AR | |
| SCHEMBL6608635 | 0.81 | AR (0.47) | DYRK1AGRM2ARKDM4EALDH1A1 | |
| SCHEMBL13964865 | 0.80 | HSD17B3 (0.43) | HASPINDYRK2ARALDH1A1 | |
| SCHEMBL8757577 | 0.79 | HASPIN (0.62) | HASPINDYRK2DYRK1AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8756541 | 0.71 | HASPIN (0.54) | HASPINDYRK2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL2797974 | 0.69 | CCNE2 (0.47) | DYRK1AKDM4EALDH1A1MAPK1HTT | |
| Hydrochloric Acid SCHEMBL8757541 | 0.69 | HASPIN (0.69) | HASPINDYRK2DYRK1A | |
| SCHEMBL9157714 | 0.68 | KMO (0.70) | ALDH1A1 | |
| SCHEMBL891123 | 0.68 | CBX7 (0.47) | KDM4EMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | UNIVERSITY OF MIAMI (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | HRH3, CHRNA4, HRH4 | HASPIN 2672/4885DYRK2 4093/4885DYRK1A 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.