Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964881 | 0.86 | KDM4E (0.36) | ARKDM4EHSD17B10PGRRORA | |
| SCHEMBL13974158 | 0.82 | HASPIN (0.48) | HASPINDYRK2GRM2ARDYRK1A | |
| SCHEMBL6608635 | 0.76 | AR (0.47) | GRM2ARDYRK1AALDH1A1KDM4E | |
| SCHEMBL13964880 | 0.68 | KDM4E (0.39) | HASPINDYRK2ARKDM4EHSD17B10 | |
| SCHEMBL23150315 | 0.66 | DYRK1A (0.72) | HASPINDYRK1AHTR2AHTR2C | |
| SCHEMBL2797974 | 0.65 | CCNE2 (0.47) | DYRK1AALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL23150395 | 0.65 | HASPIN (0.72) | HASPINDYRK1AHTR2AHTR2C | |
| SCHEMBL13964876 | 0.64 | HSD17B3 (0.44) | ARALDH1A1KDM4EPGRRORA | |
| SCHEMBL15850875 | 0.64 | ALDH1A1 (0.47) | HASPINDYRK1AALDH1A1KDM4EMAPK1 | |
| SCHEMBL12002162 | 0.63 | KDM4E (0.56) | DYRK1AALDH1A1KDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | UNIVERSITY OF MIAMI (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294808-A1 | Fluorescent Analogs of Neurotransmitters, Compositions Containing the Same and Methods of Using the Same | HRH3, CHRNA4, HRH4 | HASPIN 2672/4885DYRK2 4093/4885GRM2 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.