Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285099 | 0.90 | PPM1B (0.42) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 | |
| SCHEMBL18269160 | 0.80 | CHRNB2 (0.37) | CYP1A2CYP2C19CYP3A4CYP2D6TSHR | |
| SCHEMBL9908326 | 0.79 | CYP1A2 (0.37) | PPM1BPTPN1ALDH1A1CYP1A2MEN1 | |
| SCHEMBL21654483 | 0.79 | CYP1A2 (0.37) | PPM1BPTPN1ALDH1A1CYP1A2MEN1 | |
| SCHEMBL3694479 | 0.77 | PPM1B (0.41) | PPM1BPTPN1PPP1CCALDH1A1CYP1A2 | |
| SCHEMBL16616938 | 0.74 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 | |
| SCHEMBL22617335 | 0.74 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 | |
| SCHEMBL16617253 | 0.74 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 | |
| SCHEMBL16618144 | 0.74 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 | |
| SCHEMBL15440659 | 0.74 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158271-A1 | BRIDGED POLYCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2012-11-22 | — | — | WO | disclosed |