Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | AHCY | P23526 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964740 | 1.00 | ADORA2A (0.58) | ADORA2AADORA2BHIF1AAHCYTMEM97 | |
| SCHEMBL19190143 | 1.00 | ADORA2A (0.58) | ADORA2AADORA2BHIF1AAHCYTMEM97 | |
| SCHEMBL13964749 | 1.00 | ADORA2A (0.58) | ADORA2AADORA2BHIF1AAHCYTMEM97 | |
| SCHEMBL13964754 | 0.90 | ADORA2A (0.52) | ADORA2AADORA2BADORA3 | |
| SCHEMBL20558074 | 0.89 | P2RY12 (0.48) | ADORA2AADORA2BADORA3 | |
| SCHEMBL26435554 | 0.89 | ADORA3 (0.54) | ADORA2AADORA2BADORA3 | |
| SCHEMBL23621389 | 0.87 | LMNA (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL21063207 | 0.87 | LMNA (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL9294393 | 0.87 | LMNA (0.60) | ADORA2AADORA2BADORA3 | |
| SCHEMBL21625242 | 0.87 | LMNA (0.60) | ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012159047-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS | GILEAD SCIENCES, INC. (US) | 2012-11-22 | — | — | WO | disclosed |