SCHEMBL1397624

SCHEMBL1397624

C=C(C)c1ccccc1CC[C@@H](CC(=O)O)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CYSLTR1 Q9Y271 2/20 0.53
▸ CYSLTR2 Q9NS75 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18192989 0.89 — —
SCHEMBL1396780 0.87 — —
SCHEMBL13971703 0.87 — —
SCHEMBL9947884 0.87 — —
SCHEMBL10027690 0.87 — —
SCHEMBL12597691 0.87 — —
SCHEMBL1397230 0.87 — —
SCHEMBL1396913 0.87 — —
Hydrochloric Acid SCHEMBL14670343 0.86 — —
SCHEMBL18192986 0.85 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2288595-B1 AN IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF LAURUS LABS PRIVATE LTD (IN) 2016-11-02 — — EP disclosed
US-8367834-B2 Process for preparing Montelukast and salts thereof LAURUS LABS PRIVATE LIMITED (IN) 2013-02-05 — — US disclosed
US-20120232276-A1 PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF LAURUS LABS LIMITED (IN) 2012-09-13 — — US disclosed
US-8207343-B2 Process for preparing montelukast and salts thereof LAURUS LABS PRIVATE LIMITED (IN) 2012-06-26 — — US disclosed
US-20110112300-A1 IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF Aptuit Laurus Pvt. Ltd. (IN) 2011-05-12 — — US disclosed
EP-2288595-A2 AN IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF Aptuit Laurus Pvt Limited (IN) 2011-03-02 — — EP disclosed
WO-2009144742-A2 AN IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF APTUIT LAURUS PVT LIMITED (IN) 2009-12-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110112300-A1 IMPROVED PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF MPST, TST, CMA1 CYSLTR1 11/4885CYSLTR2 14/4885
US-20120232276-A1 PROCESS FOR PREPARING MONTELUKAST AND SALTS THEREOF MPST, TST, CMA1 CYSLTR1 12/4885CYSLTR2 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback