Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14317999 | 0.91 | TRPA1 (0.84) | TRPA1TRPV4 | |
| SCHEMBL13174922 | 0.89 | TRPA1 (1.00) | TRPA1TRPV4 | |
| SCHEMBL13834516 | 0.88 | TRPA1 (1.00) | TRPA1TRPV4 | |
| SCHEMBL474749 | 0.87 | TRPA1 (1.00) | TRPA1TRPV4 | |
| SCHEMBL13174925 | 0.83 | TRPA1 (0.89) | TRPA1TRPV4 | |
| SCHEMBL13174948 | 0.83 | TRPA1 (0.69) | TRPA1TRPV4 | |
| SCHEMBL474672 | 0.81 | TRPA1 (0.89) | TRPA1TRPV4 | |
| SCHEMBL13966937 | 0.81 | TRPA1 (0.74) | TRPA1TRPV4 | |
| SCHEMBL15158286 | 0.81 | TRPA1 (0.79) | TRPA1TRPV4 | |
| SCHEMBL474685 | 0.78 | TRPA1 (0.83) | TRPA1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295924-A1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295924-A1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | TRPA1, TRPV1, TRPV6 | TRPA1 1/4885TRPV4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.