Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.53 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 6/20 | 0.53 |
| ▸ | WDR5 | P61964 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | RBBP5 | Q15291 | 3/20 | 0.52 |
| ▸ | DPY30 | Q9C005 | 3/20 | 0.52 |
| ▸ | ASH2L | Q9UBL3 | 3/20 | 0.52 |
| ▸ | TRDMT1 | O14717 | 3/20 | 0.51 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.50 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.48 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978308 | 1.00 | SMYD3 (0.53) | SMYD3SETD2PRMT1WDR5KMT2A | |
| SCHEMBL13978307 | 0.93 | EZH2 (0.58) | SMYD3SETD2PRMT1WDR5KMT2A | |
| SCHEMBL13976436 | 0.93 | EZH2 (0.58) | SMYD3SETD2PRMT1WDR5KMT2A | |
| SCHEMBL17049511 | 0.93 | TRDMT1 (0.51) | SMYD3SETD2PRMT1WDR5KMT2A | |
| SCHEMBL13966926 | 0.89 | NSD2 (0.56) | SETD2PRMT1TRDMT1DOT1L | |
| SCHEMBL13976131 | 0.89 | ADORA2A (0.48) | — | |
| SCHEMBL13976128 | 0.88 | ADORA2A (0.49) | — | |
| SCHEMBL13978315 | 0.88 | ADORA2A (0.49) | — | |
| SCHEMBL13978385 | 0.88 | ADORA2A (0.48) | KMT2A | |
| SCHEMBL13976129 | 0.88 | ADORA2A (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | SMYD3 1521/4885SETD2 4731/4885PRMT1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.