Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12444102 | 0.92 | MTNR1A (0.43) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12515349 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL10198852 | 0.86 | MTNR1A (0.46) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19445562 | 0.85 | MTNR1A (0.38) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19445604 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12515510 | 0.84 | CYP2D6 (0.51) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19445605 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19481560 | 0.82 | MTNR1A (0.39) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12515465 | 0.82 | MTNR1A (0.43) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL19445606 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2HTTALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012158672-A2 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | POLYMEDIX, INC. (US) | 2012-11-22 | — | — | WO | disclosed |