SCHEMBL1397907

SCHEMBL1397907

Nn1ccccc1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochlorthiazide SCHEMBL7063168 0.78 CA12 (0.33)
SCHEMBL1191487 0.71 MEN1 (0.40)
SCHEMBL1205563 0.69
SCHEMBL642226 0.69
SCHEMBL5821955 0.67
SCHEMBL23912874 0.67
SCHEMBL7057595 0.67
SCHEMBL11591369 0.67
SCHEMBL446051 0.67
SCHEMBL15923447 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2340021-B1 SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES HOFFMANN LA ROCHE (CH) 2012-11-07 EP claimed
US-6028033-A FOR CONTROLLING UNDESIRED VEGETATION BASF AKTIENGESELLSCHAFT (DE) 2000-02-22 US claimed
EP-0815083-A1 N-AMINOPYRIDONE DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-01-07 EP claimed
WO-1996037471-A1 N-AMINOPYRIDONE DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-28 WO claimed
US-4101658-A Antibacterial hydrazono cephalosporins SHIONOGI & CO., LTD. (JP) 1978-07-18 US claimed
JP-7165719-A None JP disclosed
JP-7010842-A None JP disclosed
CN-116768792-B Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2024-10-18 CN disclosed
CN-116867781-A Imidazo [1,2-a ] pyridine derivatives as IRAK4 inhibitors and their use in the treatment of diseases 渤健马萨诸塞州股份有限公司 2023-10-10 CN disclosed
CN-116768792-A Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof 浙江工业大学 2023-09-19 CN disclosed
US-11570992-B2 Bicyclic compounds BASF SE (DE) 2023-02-07 US disclosed
EP-3436457-B1 BICYCLIC COMPOUNDS BASF SE (DE) 2022-07-20 EP disclosed
CN-1094028-A Selective PDE enzyme (IV) inhibitor catechol diether class PFIZER (US) 1994-10-26 CN disclosed
US-5238937-A PYRIDAZINY OR OXODIHYDROPYRIDAZINYL CHROMAN DERIVATIVES MERCK PATENT GESELLSCHAFT (DE) 1993-08-24 US disclosed
EP-0209751-B1 CEPHALOSPORIN DERIVATIVES AND BACTERICIDES CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1992-09-16 EP disclosed
EP-0489327-A1 Chroman derivatives MERCK PATENT GmbH (DE) 1992-06-10 EP disclosed
US-4758557-A Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA, LTD. (JP) 1988-07-19 US disclosed
US-4734349-A THERMOPLASTIC ELECTROSTATOGRAPHIC TONERS EASTMAN KODAK COMPANY (US) 1988-03-29 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed
US-4101658-A Antibacterial hydrazono cephalosporins SHIONOGI & CO., LTD. (JP) 1978-07-18 US disclosed