⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191487 | 0.71 | MEN1 (0.40) | — | |
| SCHEMBL642226 | 0.69 | — | — | |
| SCHEMBL1205563 | 0.69 | — | — | |
| SCHEMBL6311648 | 0.67 | — | — | |
| SCHEMBL7057597 | 0.67 | — | — | |
| SCHEMBL7057595 | 0.67 | — | — | |
| SCHEMBL9779731 | 0.67 | — | — | |
| SCHEMBL11591369 | 0.67 | — | — | |
| SCHEMBL446051 | 0.67 | — | — | |
| SCHEMBL1397907 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102285914-B | Synthesis method of 2-(1-methyl-6-carboxy-1,6-dihydropyridine)-acetic acid | WUXI APPTEC CO LTD | 2013-12-25 | — | — | CN | claimed |
| CN-101279943-A | Preparation of 6,7-dihydro-5H-cyclopenteno[b] pyridine | BEIJING HUAXI LIANHE TECHNOLOG (CN) | 2008-10-08 | — | — | CN | claimed |
| EP-3080113-B1 | FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB BIOPHARMA SPRL (BE) | 2019-09-18 | — | — | EP | disclosed |
| CN-105102445-B | Novel dihydroquinolin-2-one derivatives as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors | 豪夫迈·罗氏有限公司 | 2018-10-23 | — | — | CN | disclosed |
| US-10087179-B2 | Fused tricyclic imidazole derivatives as modulators of TNF activity | UCB BIOPHARMA SPRL (BE) | 2018-10-02 | — | — | US | disclosed |
| CN-105073732-B | The ketone derivatives of EEDQ 2 as aldosterone synthase inhibitors | 豪夫迈·罗氏有限公司 | 2017-07-21 | — | — | CN | disclosed |
| EP-3131897-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-3131896-A1 | FACTOR IXA INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20160376268-A1 | Fused Tricyclic Imidazole Derivatives As Modulators of TNF Activity | SANOFI (FR) | 2016-12-29 | — | — | US | disclosed |
| EP-3080113-A1 | FUSED TRICYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB Biopharma SPRL (BE) | 2016-10-19 | — | — | EP | disclosed |
| EP-2951180-A1 | 2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-12-09 | — | — | EP | disclosed |
| CN-102459226-B | 4-azetidinyl-1-heteroatom linked-cyclohexane antagonists of ccr2 | JANSSEN PHARMACEUTICA NV | 2014-09-17 | — | — | CN | disclosed |
| WO-2014120748-A1 | 2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-08-07 | — | — | WO | disclosed |
| CN-103958505-A | Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies | GALDERMA RES & AMP | 2014-07-30 | — | — | CN | disclosed |
| CN-102285914-B | Synthesis method of 2-(1-methyl-6-carboxy-1,6-dihydropyridine)-acetic acid | WUXI APPTEC CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-101360745-B | 8-azabicyclo[3.2.1]octane derivatives useful as monoamine reuptake inhibitors | N.V. ORGANON (NL) | 2011-12-14 | — | — | CN | disclosed |
| CN-101360745-A | 8-azabicyclo[3.2.1]octane derivatives useful as monoamine reuptake inhibitors | ORGANON NV (NL) | 2009-02-04 | — | — | CN | disclosed |
| CN-101291931-A | 9-azabicyclo [3.3.1]nonane derivatives as monoamine reuptake inhibitors | ORGANON NV (NL) | 2008-10-22 | — | — | CN | disclosed |
| CN-1531546-A | Peptide compounds | ����ҩƷ��ҵ��ʽ���� | 2004-09-22 | — | — | CN | disclosed |
| CN-1034715-A | N-cyanogen methyl-2-pyridinone insecticides | DOW CHEMICAL CO (US) | 1989-08-16 | — | — | CN | disclosed |