Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280093 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL12084549 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL9787289 | 0.74 | SMN1; SMN2 (0.74) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL12128744 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL12926334 | 0.74 | MEN1 (0.50) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL11997894 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL28908712 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL2787580 | 0.73 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL8672714 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL2689280 | 0.72 | CA4 (0.56) | SMN1; SMN2KMT2AMEN1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470735-B2 | Phenol-free phosphites | DOVER CHEMICAL CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |