Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18300399 | 0.87 | NAMPT (0.47) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL18300400 | 0.87 | NAMPT (0.47) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL10180239 | 0.86 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL17684726 | 0.86 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL17684727 | 0.86 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL8220824 | 0.83 | EPHX2 (0.60) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL12287140 | 0.83 | PRSS1 (0.46) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL24832467 | 0.83 | HDAC1 (0.48) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL3180689 | 0.81 | L3MBTL1 (0.61) | NAMPTHDAC1L3MBTL1CA1CA2 | |
| SCHEMBL24267754 | 0.81 | NAMPT (0.49) | NAMPTHDAC1L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319206-A1 | Process for Preparing Protected Amidines | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319206-A1 | Process for Preparing Protected Amidines | ASTRAZENECA AB (SE) | 2008-12-25 | — | — | US | disclosed |
| EP-1856035-B1 | PROCESS FOR PREPARAING PROTECTED AMIIDINES | ASTRAZENECA AB (SE) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319206-A1 | Process for Preparing Protected Amidines | HK1, HRH4, PYM1 | NAMPT 2167/4885HDAC1 231/4885L3MBTL1 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.