Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24832467 | 0.85 | HDAC1 (0.48) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL10180239 | 0.83 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL17684727 | 0.83 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL17684726 | 0.83 | NAMPT (0.51) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL13979656 | 0.81 | NAMPT (0.49) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL26054950 | 0.81 | NAMPT (0.45) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL8220824 | 0.80 | EPHX2 (0.60) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL18300400 | 0.79 | NAMPT (0.47) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL18300399 | 0.79 | NAMPT (0.47) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 | |
| SCHEMBL2507542 | 0.79 | NAMPT (0.60) | NAMPTHDAC1L3MBTL1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038183-A1 | EXTRACORPOREAL CLEARING TRAPS BASED ON INVERSE ELECTRON DEMAND DIELS-ALDER CYCLOADDITION FOR (PRE)-TARGETED THERAPY AND DIAGNOSTICS | RIGSHOSPITALET (DK) | 2022-02-24 | — | — | WO | disclosed |