Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980254 | 0.79 | AKR1C3 (0.42) | AKR1C3ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL13980253 | 0.78 | MTNR1A (0.41) | ALDH1A1SMN1; SMN2HTTHPGDKMT2A | |
| SCHEMBL14549499 | 0.72 | TDP1 (0.41) | ALDH1A1NPC1SMN1; SMN2RECQLKMT2A | |
| SCHEMBL14034597 | 0.69 | AKT1 (0.34) | ALDH1A1TSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10205587 | 0.69 | — | — | |
| SCHEMBL19074347 | 0.69 | AKR1C3 (0.44) | AKR1C3ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL23458002 | 0.68 | AKR1C3 (0.73) | AKR1C3ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL6433811 | 0.68 | AKR1C3 (0.73) | AKR1C3ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL7554217 | 0.66 | AKR1C3 (0.41) | AKR1C3ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL1336837 | 0.65 | GLA (0.56) | ALDH1A1NPC1SMN1; SMN2TRPM8RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | disclosed |