Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13980283 | 0.79 | AKR1C3 (0.42) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15290752 | 0.68 | MAOA (0.33) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL23458002 | 0.68 | AKR1C3 (0.73) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6433811 | 0.68 | AKR1C3 (0.73) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24062661 | 0.68 | LMNA (0.31) | — | |
| SCHEMBL13771514 | 0.67 | — | — | |
| SCHEMBL28106941 | 0.66 | AKR1C3 (0.64) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15686735 | 0.66 | AKR1C3 (0.53) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19074347 | 0.66 | AKR1C3 (0.44) | AKR1C3RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| Acetic Acid SCHEMBL6697876 | 0.65 | AKR1C3 (0.57) | AKR1C3RAB9ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997475-A2 | Composition comprising at least one substituted derivative of acetylenic carbocyanine, method of treating keratinous fibres implementing it and device | L'Oréal (FR) | 2008-12-03 | — | — | EP | disclosed |