Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3639554 | 0.86 | CACNA1G (0.42) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL3751856 | 0.86 | CACNA1G (0.42) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL3749275 | 0.85 | CACNA1G (0.41) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL3744564 | 0.85 | CACNA1G (0.41) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL3749278 | 0.85 | CACNA1G (0.41) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL13980457 | 0.84 | JAK2 (0.44) | CACNA1GCACNA1HOPRM1OPRD1OGFRL1 | |
| SCHEMBL13985723 | 0.82 | CYP3A4 (0.48) | CACNA1GCACNA1HCYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL13985721 | 0.80 | ALDH1A1 (0.40) | CACNA1GCACNA1HCYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL13985802 | 0.79 | OPRL1 (0.48) | CACNA1GCACNA1HCYP2D6OPRM1OPRL1 | |
| SCHEMBL13985629 | 0.78 | ALDH1A1 (0.43) | CACNA1GCACNA1HCYP2D6CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |