Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14136128 | 0.87 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL31090163 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL16233087 | 0.86 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL28712446 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL8297975 | 0.85 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL4977602 | 0.83 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL1667910 | 0.83 | TTR (0.68) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL824464 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL11440920 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1LMNAHTTGAA | |
| SCHEMBL97957 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2ALDH1A1LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9448237-B2 | Modified tyrosine amino acids, peptides containing them, and their use for detecting hydrolase enzyme activity | PAMGENE B.V. (NL) | 2016-09-20 | — | — | US | disclosed |
| US-20140155286-A1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PAMGENE B.V. (NL) | 2014-06-05 | — | — | US | disclosed |
| WO-2008150848-A1 | ANTIDEPRESSANT HETEROARYL DERIVATIVES OF HETEROCYCLE-FUSED BENZODIOXANS | WYETH (US) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155286-A1 | MODIFIED TYROSINE AMINO ACIDS, PEPTIDES CONTAINING THEM, AND THEIR USE FOR DETECTING HYDROLASE ENZYME ACTIVITY | PTMS, TH, TYR | SMN1; SMN2 4244/4885ALDH1A1 2926/4885LMNA 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.