Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867007 | 0.87 | SMN1; SMN2 (0.67) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL704754 | 0.87 | TTR (0.64) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL29750606 | 0.87 | TTR (0.64) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL31090163 | 0.86 | SMN1; SMN2 (0.61) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL16233087 | 0.86 | SMN1; SMN2 (0.61) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL24749642 | 0.85 | TTR (0.60) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL8297975 | 0.85 | ALDH1A1 (0.61) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL28712446 | 0.85 | SMN1; SMN2 (0.59) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL5913597 | 0.84 | LMNA (0.62) | TTRSMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL4977602 | 0.83 | ALDH1A1 (0.60) | TTRSMN1; SMN2ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486115-B1 | ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF | FRAUNHOFER GES FORSCHUNG (DE) | 2015-05-20 | — | — | EP | claimed |
| US-9939337-B2 | Deformation detection sensor and production of the same | TOYO TIRE & RUBBER CO., LTD. (JP) | 2018-04-10 | — | — | US | disclosed |
| US-20170288283-A1 | SENSOR FOR DETECTING DEFORMATION OF SEALED SECONDARY BATTERY | TOYO TIRE & RUBBER CO., LTD. (JP) | 2017-10-05 | — | — | US | disclosed |
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |
| EP-3085572-A1 | DEFORMATION DETECTION SENSOR AND PRODUCTION OF THE SAME | Toyo Tire & Rubber Co. Ltd. (JP) | 2016-10-26 | — | — | EP | disclosed |
| US-20160305831-A1 | DEFORMATION DETECTION SENSOR AND PRODUCTION OF THE SAME | TOYO TIRE & RUBBER CO., LTD. (JP) | 2016-10-20 | — | — | US | disclosed |
| US-9265768-B2 | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-02-23 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| EP-2486115-B1 | ELECTRORHEOLOGIC FLUID COMPRISING ORGANIC SUBSTANCES THAT CAN BE DOPED AND USE THEREOF | FRAUNHOFER GES FORSCHUNG (DE) | 2015-05-20 | — | — | EP | disclosed |
| CN-1291970-C | Method for preparing combretastatins | AVENTIS PHARMA SA (FR) | 2006-12-27 | — | — | CN | disclosed |
| US-7049342-B2 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2006-05-23 | — | — | US | disclosed |
| CN-1646476-A | Method for preparing combretastatins | AVENTIS PHARMA SA (FR) | 2005-07-27 | — | — | CN | disclosed |
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6759555-B2 | CONDENSING (3,4,5-TRIMETHOXYBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE WITH 3-NITRO-4-METHOXYBENZALDEHYDE, REDUCING THE NITRO INTERMEDIATE TO FORM 2-METHOXY-5-(2-(3,4,5-TRIMETHOXYPHENYL)-ETHENYL)ANILINE | AVENTIS PHARMA S.A. (FR) | 2004-07-06 | — | — | US | disclosed |
| US-20030220404-A1 | Process for the preparation of combretastatins | AVENTIS PHARMA S.A. (FR) | 2003-11-27 | — | — | US | disclosed |
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-1285908-A1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187068-A1 | Substituted phenylpropionic acid derivatives | PPARA, PPARG, PPARD | TTR 2531/4885SMN1; SMN2 4657/4885ALDH1A1 429/4885 |
| US-20030220404-A1 | Process for the preparation of combretastatins | TGFB2, HMGCR, TGFB1 | TTR 794/4885SMN1; SMN2 1402/4885ALDH1A1 2753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.