Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 12/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982122 | 0.92 | PTGES (0.34) | PTGESP2RX7CHRM4EPHX2NR1H4 | |
| SCHEMBL3802046 | 0.89 | CYP3A4 (0.39) | PTGESP2RX7EPHX2 | |
| SCHEMBL13982199 | 0.87 | PTGES (0.36) | PTGES | |
| SCHEMBL13982167 | 0.87 | PTGES (0.35) | PTGESP2RX7 | |
| SCHEMBL13982396 | 0.85 | PTGES (0.33) | PTGES | |
| SCHEMBL13982250 | 0.84 | PTGES (0.38) | PTGESP2RX7EPHX2NR1H4 | |
| SCHEMBL13982397 | 0.83 | L3MBTL1 (0.35) | PTGESP2RX7EPHX2NR1H4 | |
| SCHEMBL13982110 | 0.83 | PTGES (0.34) | PTGESP2RX7 | |
| SCHEMBL3028560 | 0.81 | CYP3A4 (0.39) | PTGESP2RX7EPHX2 | |
| SCHEMBL13981694 | 0.81 | PTGES (0.33) | PTGESP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |