Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982214 | 0.91 | LMNA (0.36) | EPHX2NR1H4L3MBTL1PTGESLMNA | |
| SCHEMBL13982369 | 0.88 | RORC (0.35) | EPHX2PTGESLMNAP2RX7 | |
| SCHEMBL13982393 | 0.88 | CYP3A4 (0.33) | EPHX2NR1H4L3MBTL1PTGESLMNA | |
| SCHEMBL13982082 | 0.88 | LMNA (0.36) | EPHX2PTGESLMNAKLKB1MAP4K1 | |
| SCHEMBL13981834 | 0.88 | CYP3A4 (0.36) | EPHX2PTGESLMNAP2RX7KLKB1 | |
| SCHEMBL3028963 | 0.88 | CYP3A4 (0.42) | EPHX2NR1H4L3MBTL1PTGESLMNA | |
| SCHEMBL13982326 | 0.87 | LMNA (0.34) | L3MBTL1PTGESLMNAKLKB1MAP4K1 | |
| SCHEMBL13982448 | 0.87 | LMNA (0.34) | EPHX2NR1H4L3MBTL1PTGESLMNA | |
| SCHEMBL13982327 | 0.86 | LMNA (0.33) | EPHX2NR1H4L3MBTL1PTGESLMNA | |
| SCHEMBL13982171 | 0.86 | RORC (0.36) | PTGESKLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |