Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982697 | 0.86 | MAPT (0.49) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL13982767 | 0.83 | GUSB (0.41) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL13982790 | 0.83 | PTGER1 (0.46) | MAPTKMT2ARAB9ANPC1MEN1 | |
| SCHEMBL13982786 | 0.82 | MAPT (0.47) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL13982736 | 0.76 | NPC1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL13982792 | 0.74 | MAPT (0.45) | MAPTALDH1A1KMT2ARAB9AMEN1 | |
| SCHEMBL13982789 | 0.74 | SMN1; SMN2 (0.46) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL25725903 | 0.73 | AKR1C3 (0.55) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL13982748 | 0.73 | RAB9A (0.43) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL16175317 | 0.72 | MAPT (0.46) | MAPTALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |