Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982789 | 0.91 | SMN1; SMN2 (0.46) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13982773 | 0.89 | PTPN1 (0.48) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13982748 | 0.88 | RAB9A (0.43) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13982697 | 0.85 | MAPT (0.49) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13983269 | 0.85 | CRHR1 (0.43) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13982743 | 0.81 | PTGDR2 (0.42) | RAB9APTPN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13983250 | 0.81 | MAPT (0.42) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13982742 | 0.81 | PTGDR2 (0.42) | RAB9APTPN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13982786 | 0.76 | MAPT (0.47) | RAB9AKMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13983162 | 0.76 | RAB9A (0.48) | RAB9APTPN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |