Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983256 | 0.98 | P2RX7 (0.32) | PIK3CA | |
| SCHEMBL13983285 | 0.94 | — | — | |
| SCHEMBL13983278 | 0.90 | DHODH (0.34) | CYP3A4CYP2D6CYP2C9CYP2C19F10 | |
| SCHEMBL13983254 | 0.88 | TRPV1 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13983255 | 0.87 | FFAR1 (0.35) | CYP3A4CYP2D6CYP2C9CYP2C19DHODH | |
| SCHEMBL13983252 | 0.85 | TRPV1 (0.37) | — | |
| SCHEMBL13983280 | 0.85 | BRD9 (0.33) | PIK3CACYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13983283 | 0.84 | JAK2 (0.33) | DHODH | |
| SCHEMBL13983522 | 0.83 | FFAR1 (0.32) | PIK3CA | |
| SCHEMBL13983272 | 0.82 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008151927-A2 | 6-N-SUBSTITUTED BENZ IMIDAZOLE DERIVATIVES AS ACID PUMP ANTAGONISTS | NYCOMED GMBH (DE) | 2008-12-18 | — | — | WO | disclosed |