Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861463 | 1.00 | MAPT (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14347211 | 1.00 | MAPT (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14127793 | 0.90 | MAPT (0.57) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25686054 | 0.83 | CNR2 (0.51) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18752408 | 0.82 | GPR119 (0.49) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15205475 | 0.82 | GRIN2D (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17316509 | 0.82 | GRIN2D (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17316304 | 0.82 | GRIN2D (0.48) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13724794 | 0.82 | GPR119 (0.49) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18752394 | 0.82 | GPR119 (0.49) | MAPTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156718-A1 | CETP INHIBITORS DERIVED FROM BENZOXAZOLE ARYLAMIDES | MERCK & CO., INC. (US) | 2008-12-24 | — | — | WO | disclosed |