Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012858 | 0.92 | — | — | |
| SCHEMBL15382443 | 0.82 | HDAC1 (0.53) | HIF1AEPAS1HDAC1NPC1RAB9A | |
| SCHEMBL13267211 | 0.79 | KMT2A (0.60) | HIF1AEPAS1NPC1RAB9AALDH1A1 | |
| SCHEMBL3011300 | 0.76 | MMP13 (0.51) | HIF1AEPAS1 | |
| SCHEMBL13267170 | 0.75 | HRH3 (0.50) | NPC1RAB9AALDH1A1KDM4EHRH3 | |
| SCHEMBL3015924 | 0.73 | KMT2A (0.57) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL28162775 | 0.71 | KMT2A (0.58) | HIF1AEPAS1NPC1RAB9AALDH1A1 | |
| SCHEMBL3012862 | 0.71 | ACACB (0.42) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL1109236 | 0.71 | HDAC1 (0.53) | HIF1AEPAS1HDAC1NPC1RAB9A | |
| SCHEMBL14400854 | 0.70 | KMT2A (0.51) | HIF1AEPAS1HDAC1NPC1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154642-A2 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2008-12-18 | — | — | WO | disclosed |