Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28162775 | 0.92 | KMT2A (0.58) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL3015924 | 0.91 | KMT2A (0.57) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28162774 | 0.87 | KMT2A (0.56) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL13984586 | 0.79 | HIF1A (0.47) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL10272436 | 0.78 | KMT2A (0.77) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL18023372 | 0.76 | KMT2A (0.41) | KMT2A | |
| SCHEMBL10184791 | 0.76 | KMT2A (0.64) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL13984508 | 0.75 | KMT2A (0.56) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL7705653 | 0.75 | ALDH1A1 (0.77) | KMT2AALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL13267170 | 0.74 | HRH3 (0.50) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | KMT2A 4779/4885ALDH1A1 687/4885NPC1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.