Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12790215 | 0.94 | HPGDS (0.51) | HPGDSMAPTGAAALDH1A1KMT2A | |
| SCHEMBL12790199 | 0.88 | MAPT (0.49) | HDAC6HPGDSMAPTGAAALDH1A1 | |
| SCHEMBL699276 | 0.83 | CAMK2D (0.50) | HDAC6CDK2MAPK8 | |
| SCHEMBL3688533 | 0.82 | CSNK2A1 (0.76) | HDAC6MAPTGAAALDH1A1KMT2A | |
| SCHEMBL12790443 | 0.81 | PRKD3 (0.52) | HDAC6MAPTGAAALDH1A1KMT2A | |
| SCHEMBL12790174 | 0.80 | PRKD3 (0.52) | HDAC6MAPTGAAALDH1A1KMT2A | |
| SCHEMBL3689066 | 0.80 | HDAC6 (0.54) | HDAC6MAPTGAAALDH1A1KMT2A | |
| SCHEMBL1684736 | 0.79 | MAPT (0.68) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL12791070 | 0.79 | MAPT (0.49) | MAPTGAAALDH1A1KMT2AHTT | |
| SCHEMBL12790205 | 0.79 | PRKD3 (0.50) | HDAC6MAPTGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002534-A1 | IMIDAZOPYRIDINYL THIAZOLYL HISTONE DEACETYLASE INHIBITORS | GILEAD COLORADO, INC. (US) | 2008-12-31 | — | — | WO | disclosed |