Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 7/20 | 0.34 |
| ▸ | DRD1 | P21728 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742542 | 0.87 | F3 (0.46) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL2742545 | 0.71 | EP300 (0.47) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL2742629 | 0.69 | F3 (0.73) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL24697074 | 0.66 | F3 (0.67) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL2742544 | 0.66 | DRD1 (0.60) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL16772366 | 0.60 | DRD1 (0.48) | F3DRD1DRD2LMNACYP1A2 | |
| SCHEMBL16774958 | 0.60 | DRD1 (0.46) | F3DRD1DRD2LMNACYP1A2 | |
| SCHEMBL22005137 | 0.58 | PARP1 (0.40) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL14208062 | 0.58 | DRD1 (0.46) | F3DRD1DRD2KMT2ALMNA | |
| SCHEMBL910003 | 0.56 | F3 (0.80) | F3DRD1DRD2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009002873-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING LIPID LEVELS | CVI PHARMACEUTICALS LIMITED (KY) | 2008-12-31 | — | — | WO | disclosed |