Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | F3 | P13726 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51099 | 0.72 | HTR1A (0.58) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL51308 | 0.72 | HTR1A (0.58) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL21255278 | 0.72 | HTR1A (0.58) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL51178 | 0.72 | HTR1A (0.58) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL51164 | 0.72 | HTR1A (0.58) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL21255665 | 0.71 | ACHE (0.39) | PARP1DRD1DRD2DRD3F3 | |
| Hydrochloric Acid SCHEMBL50121 | 0.71 | HTR1A (0.56) | DRD1DRD2DRD3F3DRD5 | |
| SCHEMBL51300 | 0.71 | DRD2 (0.56) | DRD1DRD2DRD3F3DRD5 | |
| Hydrochloric Acid SCHEMBL50938 | 0.71 | HTR1A (0.56) | DRD1DRD2DRD3F3DRD5 | |
| Hydrochloric Acid SCHEMBL253095 | 0.71 | HTR1A (0.56) | DRD1DRD2DRD3F3DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653210-A1 | TREATMENT OF DYSKINESIA RELATED DISORDERS | H. Lundbeck A/S (DK) | 2020-05-20 | — | — | EP | disclosed |