SCHEMBL910003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29999635	1.00	F3 (0.80)	F3DRD1DRD2CYP1A2CYP3A4
	SCHEMBL29999816	0.89	F3 (0.72)	F3DRD1DRD2CYP1A2CYP3A4
	SCHEMBL910294	0.89	F3 (0.72)	F3DRD1DRD2CYP1A2CYP3A4
	SCHEMBL2742658	0.89	F3 (0.75)	F3DRD1DRD2CYP1A2CYP3A4
	Tetrahydroberberine SCHEMBL2786492	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4
	Tetrahydroberberine SCHEMBL30484836	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4
	Tetrahydroberberine SCHEMBL30302597	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4
	Canadine SCHEMBL29365824	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4
	Tetrahydroberberine SCHEMBL232164	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4
	Canadine SCHEMBL432394	0.89	F3 (1.00)	F3DRD1DRD2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.