Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | MGLL | Q99685 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985287 | 0.91 | KMT2A (0.56) | CA12CA1CA2CA9MAPT | |
| SCHEMBL203521 | 0.89 | SMN1; SMN2 (0.55) | CA12CA1CA2CA9MAPT | |
| SCHEMBL30570218 | 0.80 | FURIN (0.70) | CA12CA1CA2CA9MAPT | |
| SCHEMBL13941446 | 0.80 | FAAH (0.52) | MAPTKMT2AMEN1FAAHMGLL | |
| SCHEMBL3633396 | 0.77 | NPC1 (0.84) | CA12CA1CA2CA9MAPT | |
| SCHEMBL31054222 | 0.77 | NPC1 (0.69) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL13431057 | 0.76 | PLK4 (0.57) | FAAHMGLLLMNA | |
| SCHEMBL13160507 | 0.76 | PLK4 (0.57) | FAAHMGLLLMNA | |
| SCHEMBL13941402 | 0.76 | PLK4 (0.57) | FAAHMGLLLMNA | |
| SCHEMBL13941618 | 0.75 | FAAH (0.48) | MAPTKMT2AMEN1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |