Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | MGLL | Q99685 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985290 | 0.91 | CA12 (0.56) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL203521 | 0.84 | SMN1; SMN2 (0.55) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL24166921 | 0.80 | NPC1 (0.69) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL10155599 | 0.79 | ALDH1A1 (0.78) | KMT2AALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL15849841 | 0.79 | PLK4 (0.53) | FAAHMGLLBCHE | |
| SCHEMBL8686673 | 0.78 | ALDH1A1 (0.68) | KMT2AALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL10155589 | 0.76 | ALDH1A1 (0.62) | KMT2AALDH1A1CA2NPC1MAPT | |
| SCHEMBL3885202 | 0.76 | EPHX2 (0.62) | KMT2AALDH1A1CA2CA9CA12 | |
| SCHEMBL18814508 | 0.75 | KMT2A (0.67) | KMT2AALDH1A1CA1CA2CA9 | |
| SCHEMBL13941618 | 0.74 | FAAH (0.48) | KMT2AALDH1A1MAPTFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156573-A1 | KINASE INHIBITORS, COMPOSITIONS THEREOF, AND METHODS OF USE THEREWITH | PROVID PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |