Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.58 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.58 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.58 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.58 |
| ▸ | TNF | P01375 | 2/20 | 0.58 |
| ▸ | IL1B | P01584 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19359328 | 0.99 | CRBN (0.57) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL12072673 | 0.91 | CRBN (0.56) | CRBNIKZF3DDB1IKZF1TNF | |
| Hydrochloric Acid SCHEMBL19359338 | 0.90 | CRBN (0.55) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL25834806 | 0.89 | CRBN (0.54) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL25834470 | 0.89 | CRBN (0.56) | CRBNIKZF3DDB1IKZF1TNF | |
| Hydrochloric Acid SCHEMBL19359329 | 0.88 | CRBN (0.53) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL25834811 | 0.88 | CRBN (0.53) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL25834813 | 0.88 | CRBN (0.55) | CRBNIKZF3DDB1IKZF1TNF | |
| SCHEMBL25834819 | 0.87 | CRBN (0.57) | CRBNIKZF3DDB1IKZF1TNF | |
| Hydrochloric Acid SCHEMBL19359321 | 0.87 | CRBN (0.52) | CRBNIKZF3DDB1IKZF1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364243-A1 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2023-07-20 | — | — | US | disclosed |
| US-7470724-B2 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. (US) | 2008-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364243-A1 | CANCER-SELECTIVE TARGET DEGRADATION BY TARGETING GROUP CAGED PROTACS | ADRM1, MYC, SKP2 | CRBN 244/4885IKZF3 3659/4885DDB1 2620/4885 |
| US-20230226035-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | CD4, CRBN, GZMB | CRBN 2/4885IKZF3 274/4885DDB1 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.