Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12943042 | 0.88 | PLA2G2A (0.58) | DHODHPLA2G2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13985407 | 0.85 | ITGB1 (0.49) | DHODHITGB1ITGA4PLA2G2APDE10A | |
| SCHEMBL4796184 | 0.83 | HDAC3 (0.56) | KDM4EALDH1A1HPGDCYP1A2HSD17B10 | |
| SCHEMBL3036200 | 0.82 | KDM4E (0.56) | DHODHPLA2G2APDE10AKDM4EALDH1A1 | |
| SCHEMBL13633717 | 0.82 | PDE10A (0.42) | DHODHITGB1ITGA4PLA2G2APDE10A | |
| SCHEMBL3908402 | 0.81 | CYSLTR2 (0.51) | DHODHPLA2G2A | |
| SCHEMBL29042714 | 0.78 | ESR1 (0.55) | DHODHPLA2G2APDE10AKDM4EALDH1A1 | |
| SCHEMBL30496184 | 0.78 | ESR1 (0.55) | DHODHPLA2G2APDE10AKDM4EALDH1A1 | |
| SCHEMBL3968662 | 0.78 | DHODH (0.43) | DHODHITGB1ITGA4PLA2G2APDE10A | |
| SCHEMBL10091837 | 0.77 | APP (0.47) | DHODHKDM4EALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |