Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985404 | 0.85 | DHODH (0.58) | ITGB1ITGA4PLA2G2ADHODHMAPT | |
| SCHEMBL4798901 | 0.83 | HDAC3 (0.50) | CYP3A4ALOX5PPARGKMT2AMEN1 | |
| SCHEMBL13979974 | 0.74 | TP53 (0.40) | ITGB1ITGA4PLA2G2ADHODHMAPT | |
| SCHEMBL14366211 | 0.74 | SLC2A1 (0.52) | PLA2G2AMAPTGAAKMT2AMEN1 | |
| SCHEMBL12943042 | 0.73 | PLA2G2A (0.58) | PLA2G2ADHODHMAPTALDH1A1POLB | |
| SCHEMBL8050448 | 0.72 | PLA2G2A (0.50) | PLA2G2ADHODHMAPTALDH1A1POLB | |
| SCHEMBL29042714 | 0.72 | ESR1 (0.55) | PLA2G2ADHODHMAPTPDE10AALDH1A1 | |
| SCHEMBL30496184 | 0.72 | ESR1 (0.55) | PLA2G2ADHODHMAPTPDE10AALDH1A1 | |
| SCHEMBL168796 | 0.72 | TSHR (0.58) | ITGB1ITGA4MAPTNPSR1ALDH1A1 | |
| SCHEMBL7046745 | 0.71 | MAPT (0.49) | DHODHMAPTNPSR1PDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459284-B2 | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-12-02 | — | — | US | disclosed |