Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24611668 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL8403198 | 0.82 | TAAR1 (0.50) | CYP3A4TAAR1MAPK1SLC18A2SIGMAR1 | |
| SCHEMBL16266018 | 0.77 | TDP1 (0.50) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL8399619 | 0.77 | TDP1 (0.50) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL8164864 | 0.77 | TRPA1 (0.50) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL4228132 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| SCHEMBL8722485 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4CYP3A4CYP2D6 | |
| E968 SCHEMBL9527553 | 0.75 | TDP1 (0.56) | KCNH2TSHRTAAR1TDP1SMN1; SMN2 | |
| SCHEMBL8150050 | 0.75 | TAAR1 (0.46) | CYP3A4TAAR1MAPK1SLC18A2SIGMAR1 | |
| SCHEMBL13986001 | 0.74 | CTSK (0.56) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462746-B2 | Amino polyols and amino sugars | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2008-12-09 | — | — | US | disclosed |