Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | CD14 | P08571 | 1/20 | 0.43 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 4/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PTPRB | P23467 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.39 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545628 | 0.89 | CD69 (0.51) | TLR4CD14LY96CYP19A1PTPRC | |
| SCHEMBL16545616 | 0.78 | MAOB (0.38) | TLR4CD14LY96CYP19A1MAPT | |
| SCHEMBL16545618 | 0.75 | CD69 (0.56) | MAPTPTPN2PTPN1PTPN11RAB9A | |
| SCHEMBL13987037 | 0.74 | TLR4 (0.49) | TLR4CD14LY96PTPRCPTPN2 | |
| SCHEMBL13987039 | 0.73 | TLR4 (0.51) | TLR4CD14LY96MAPTPOLB | |
| SCHEMBL7933242 | 0.72 | HTT (0.55) | CYP19A1MAPTPOLBHTTRAB9A | |
| Methyl Alcohol SCHEMBL28153624 | 0.72 | CYP19A1 (0.50) | CYP19A1MAPTPOLBHTTRAB9A | |
| SCHEMBL14118062 | 0.71 | CYP19A1 (0.49) | CYP19A1MAPTPOLBHTTRAB9A | |
| SCHEMBL28676524 | 0.71 | ALDH1A1 (0.50) | CYP19A1MAPTPOLBHTTRAB9A | |
| SCHEMBL7933239 | 0.71 | CYP19A1 (0.52) | CYP19A1MAPTPOLBHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465820-B2 | Abiotic heparin antagonists | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2008-12-16 | — | — | US | disclosed |
| US-20070082951-A1 | Abiotic heparin antagonists | CONSIGLIO NAZIONALE DELLE RICECHE (IT) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082951-A1 | Abiotic heparin antagonists | CALR, NPSR1, CANX | TLR4 696/4885CD14 2607/4885LY96 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.