Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD69 | Q07108 | 3/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | CD14 | P08571 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.39 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPRB | P23467 | 3/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545618 | 0.90 | CD69 (0.56) | CD69ELANEPTGDR2PTPN2PTPN1 | |
| SCHEMBL13987038 | 0.89 | TLR4 (0.43) | TLR4CD14LY96GSTA1GSTP1 | |
| SCHEMBL16545621 | 0.83 | CD69 (0.47) | CD69ELANEPTGDR2TLR4CD14 | |
| SCHEMBL16545626 | 0.78 | CD69 (0.83) | CD69ELANETLR4CD14LY96 | |
| SCHEMBL2059437 | 0.74 | PTGDR2 (0.47) | CD69ELANEPTGDR2PTPRBTHRA | |
| SCHEMBL4072031 | 0.72 | KDM4E (0.51) | PTGDR2 | |
| SCHEMBL16545616 | 0.70 | MAOB (0.38) | CD69ELANETLR4CD14LY96 | |
| SCHEMBL16545625 | 0.69 | CD69 (0.63) | CD69ELANEPTGDR2PTPN1 | |
| SCHEMBL8625852 | 0.69 | PTGDR2 (0.50) | PTGDR2PTPRBCYP19A1THRATHRB | |
| SCHEMBL2184946 | 0.68 | CD69 (1.00) | CD69ELANEPTGDR2TLR4CD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITÉ PARIS CITÉ (FR) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | CD69 672/4885ELANE 311/4885PTGDR2 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.