Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987983 | 0.91 | NPSR1 (0.47) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4860213 | 0.91 | CASP3 (0.50) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL13988010 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4859795 | 0.90 | CASP3 (0.49) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4852531 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4851844 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4863090 | 0.89 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4850112 | 0.88 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4850101 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTRXFP1USP2 | |
| SCHEMBL4855459 | 0.88 | MAPT (0.47) | ALDH1A1KDM4EMAPTRXFP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |