Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854070 | 0.91 | TRIM24 (0.43) | DRD4MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4860516 | 0.91 | ACHE (0.44) | DRD4ACHEDRD2MAPTMEN1 | |
| SCHEMBL4855332 | 0.91 | ACHE (0.41) | DRD4ACHEDRD2MAPT | |
| SCHEMBL4854054 | 0.90 | ACHE (0.40) | DRD4ACHEDRD2MAPTALDH1A1 | |
| SCHEMBL4861455 | 0.90 | ACHE (0.44) | DRD4ACHEDRD2MAPTMEN1 | |
| SCHEMBL4859150 | 0.90 | THRB (0.45) | DRD4MAPTMEN1KMT2A | |
| SCHEMBL4860111 | 0.90 | ACHE (0.38) | DRD4ACHEDRD2MAPTMEN1 | |
| SCHEMBL4863112 | 0.89 | ACHE (0.44) | DRD4ACHEMAPT | |
| SCHEMBL4861185 | 0.88 | TRIM24 (0.45) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL4851825 | 0.88 | MAPT (0.42) | DRD4ACHEDRD2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |