Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13987291 | 0.99 | HTR1A (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL4853332 | 0.99 | HTR1A (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL4852128 | 0.98 | HTR1A (0.48) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| SCHEMBL13987700 | 0.95 | ACHE (0.50) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL4854005 | 0.94 | ACHE (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| SCHEMBL13987345 | 0.94 | ACHE (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| Hydrochloric Acid SCHEMBL4861515 | 0.93 | ACHE (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| SCHEMBL13987313 | 0.90 | NPC1 (0.50) | ACHESIGMAR1 | |
| SCHEMBL6035333 | 0.89 | ACHE (0.57) | HTR1ADRD2HTR2AHTR2CHRH1 | |
| SCHEMBL4863050 | 0.89 | ACHE (0.49) | HTR1ADRD2HTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7462628-B2 | Preventives/remedies for urinary disturbance | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-09 | — | — | US | disclosed |